Niemann Pick Disease

I. Overview:

Niemann Pick Disease is a lipid storage disorder closely related to Alzheimer’s disease. It is a very serious condition that causes a variety of health issues, disabilities, and even death. Described below are the three types of Niemann Pick Disease: Type A, B, and C.

Type A: problems include liver enlargement and spleen enlargement from excessive cholesterol, a byproduct of the condition. Another symptom is the failure to gain weight and certain neurological problems.

Type B:

problems include retardation, lung failures, brain disorders, and blood disorders. These problems can start in newborns around 3 months old. People with type B can grow up to be adults.

Type C: problems include liver disease, trouble breathing, seizures, and n inability to move their eyes vertically. Type C consists of both Types A and B. Once the disease is diagnosed the average person has a 7 to 10 year life span.

II. Gene Related Acquisition of the Disease:

Patients likely to develop Niemann Pick Disease will have inherited it in an autosomal recessive pattern, Put simply, this means both copies of the gene in each cell have mutations. The parents of a kid with this condition each carry one copy of the mutated gene. The parents do not show any sign or symptoms of the Niemann-Pick Disease. Most often this deadly combination comes from parents who are closely related. The disorder, however, is not sex linked.

III. Diagnosis and Life Span:

Type A: often noticed when a person is a baby around 3 months of age. Many of these babies do not make it passed the age of three.

Type B: often noticed at around 6 months of age. Many of these infants can make it to be adults.

Type C: often noticed at birth or at an older age. When symptoms arise, the patient usually lives no more than 10 additional years.

IV. Early Diagnosis:

Fetus: Parents can check the fetus chromosomes for irregularities prior to birth.

Adult: Parents themselves can have a DNA test to see if they have any mutated chromosomes- this is especially important if they are closely related.

V. High Risk Candidates:

Types A and B occur in all races.

Type A disease occurs more frequently in people of Ashkenazi Jewish descent. Type B occurs higher in the Maghreb region of North Africa, Saudi Arabia and in People of Turkish descent that are all closely related. People such as these descendants should be tested so that we don’t keep having babies that can be carriers and the disease or simply refrain from having babies with close or distant relatives.

VI. Autosomal Recessive Inheritance Graph:
VI. Resources:

a) The Niemann-Pick Disease Foundation
b) http://www.youtube.com/watch?v=ME-LFneuDZk
c) Genetic Home Reference.com
e) National Niemann-Pick Disease Foundation Inc.com
f) Genetic Disorder Testing.com

Blog Post# 6

1. What was your favorite Geology topic this year? Why?
When we learned about volcanoes because I think it cool how lava can melt almost anything.

2. What was your favorite Meteorology topic this year? Why?
When we learned about clouds because now I know what kind of clouds are there when there is a storm.

3. What was your favorite Astronomy topic this year? Why? (Include a picture for #1, #2, OR #3)
When we learned about how the universe formed and about black/worm holes because I like to discuse about time travel and space.

4. What grade do you think you earned on the Final Exam? What did you do to prepare? Is there anything that you wish you had done differently?
I think I got at least a 80. I study my cross words and the online quizzes on quizstar. No

Blog Post#5

Blog Post# 4

1. What made the Big Bang "bang?" In other words, why didn't the universe just stay in a tiny little sphere the size of a golfball? More details = more points.
Because they just started to blow up and take up more space. But I am going with the Dunn theory which says we will all get sucked up into a black hole and the black hole will fill up and explode again and so on.

2. What do you think would happen if you went into a black hole? Scientists only know what happens until you get to the event horizon. Anything beyond that is really just an educated guess. More details = more points.
I think that we wouldn't survive. I think we would get crushed up into pieces but the black hole would be filled up eventually. I think the black hole would be like a blender.

3. Tell me what you think about worm holes? When you pass through one, where do you go? WHEN do you go? More details = more points.
I think that they can be real but they have a limit like i think they wouldn't be able to take you back in time but into the future. But if it doesn't take you into any point in time i think it could take you into a different dimension, but if i could go through a worm hole i would want to go into the future to see what would happen to the world later.

Blog Post# 2

1. What is the primary gas in the Jovian atmospheres?
The main gas in the Jovian planets is Hydrogen

2. What is the primary gas in Mars and Venus?
Mars primary gas is carbon dioxide and for Venus is nitrogen

3. If you had to visit one planet, which would it be? Why? Give me a solid paragraph. (consider many factors such as location, temperature, atmosphere composition, and anything else you you feel is important).
I would want to visit Mars because its still close to home so I could make it back faster to earth

Blog Post# 1

1) Black holes- Black holes are places where ordinary gravity has become so extreme that it overwhelms all other forces in the Universe. Once inside, nothing can escape a black hole's gravity — not even light.

2) Worm holes- Wormholes arise as solutions to the equations of Einstein's general theory of relativity. Its just like time travel

3) Milky Way Galaxy- The Milky Way has been described as a serpent or a river, and in Sweden they call our galaxy Vinter Gatan

4) Kuiper Belt- It is located beyoned neptune. It was named after astronomer Gerard Kuiper.


5) Pluto- Pluto orbits beyond the orbit of Neptune (usually). It is much smaller than any of the official planets and now classified as a "dwarf planet". Pluto is smaller than seven of the solar system's moons

Blog post# 6

1. Which blog was your best this quarter? Why?Blog post# 5 because I really enjoyed doing it and it looks really cool.

2. What topic did you enjoy learning about the most (from chapter 17-20)? Why? Include a picture.Wind speed because I liked doing the lab about making a anemometer to measure wind speeds and our recession field trip outside.

3. What grade do you deserve for your 3rd Quarter Blogs? (Keep in mind some basic math. If you only did 3 out of 6 of them you cannot earn above a 50%.)I think i deserve a 93 because I have been making 85-91 and been consistent with it so that I can make a A in this class.

Blog Post#5

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Blog post# 4

1. Check out Fayetteville's pollen forecast. Which is affecting us the most right now: tree, grass, or weed pollen? Specifically, which trees, grasses, or weeds?

It is trees. Oak tress

2. "You're Surrounded by Pollen," so read this article. What is needed for a "perfect storm" of pollen?

Its a long winter plus a dry windy weather

3. Choose a microscopic image of pollen. Which one looks the best to you? Why? Where is this pollen commonly found? Write a paragraph in your own words explaining this specific type of pollen. Include a cool-looking picture. You may need to use other websites to help you.

Helian looks like me the most. Because its really spikey and cool looking like me. Its most commonly found in flowers.

Trees are the earliest pollen producers, releasing their pollen as early as January in the Southern states and as late as May or June in the Northern states. Trees can aggravate your allergy whether or not they are on your property, since trees release large amounts of pollen that can be distributed miles away from the originial source.

Blog post# 3

1) The five main states of matter are Solids, liquids, gases, plasmas, and Bose-Einstein condensates are all different states of matter.
2) To make a gas into a plasma you add energy.
3) The temperuters at absolute zero in Farenheit, Celsius, and Kelvin are K=0. C=-273.15 F=-459.67.
4) The temprture in space is 0 in Kelvin
5) I think plasma would look like a bright green light. I dont think it would have a smell. I would also think it would be to hot to touch. And I think if you tasted it you would die but ultimatly i would think it would taste like dog food. I think Bose-Einstein Condensates would look like ice(kind of bluish). I think it would smell like ferbreez. I think it would be to cold to touch and it would burn you. Also I think you would also die from eating it but I would have to say CAT food!

blog post# 2

1) One is geothermal, the second is solar photovoltaic power systems, the last is rainwater collections.
2) Geothermal is when underground pipes it heats or cools your house. photovoltaic power is basically solar energy. rainwater collections is water collected from gutters ect. so they can re use it.
3) I chose a green economy for earth day
4) The problem for green economy is that most people don't want it.
5) To help make people go for it is tell people how you can benefit from it. Also i can give out pamphlets show how much you can save or benefit from it. And if i really wanted to get into it i can join a group and walk around with signs saying switch to a green economy.

Blog post#1

1. Which hurricane did you choose? I choosed Hurricane Dennis 2005

2. What category was it on the Saffir-Simpson scale? It was a category 4 on the Saffir scale.

3. Tell its story. It moved westward across the coast of Africa.

4. How many lives were lost? How much damage did it cause ($)? Dennis caused 42 deaths - 22 in Haiti, 16 in Cuba, 3 in the United States, and 1 in Jamaica.

5. Include at least one picture.

Blog Post# 7

1)I think it was the Wordle one. I think it was because it was fun and easy.
2)I think I deserve a A for my blogs because I did all of them and I didn't do them scrubby.
3)My Favorite topic this quarter was chapter 9. Because it was interesting to learn about plate tonics. Also about how we learned about how continent drift was crap.

Blog Post# 6

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blog post#5

1) Pick one of the articles you read. List the Name of the article and publisher.
Chinese earthquake: Giant pandas rescued. telegraph

2. What was the author's thesis? (insert the quote)
Hundreds of giant pandas had to be rescued as the Chinese Earthquake devastated their breeding grounds

3. Do you agree with their thesis? Why or why not?
I agree because because it saving an almost extinct specious.

Web quest

http://docs.google.com/View?id=ddxrcnfp_1c9gk5jgc

Blog post #4

1)William Michael Bright: Zoologist, Biologist he contributed by An Educational and Social Study of Negroes Who Have Earned Doctoral Degrees in Course, 1876-1943.
2)Lonnie Johnson created the Super Soaker, Garrett Morgan created the Gas Mask, and Tom J. Marshal created Fire Extinguisher
3)Otis Boykin .Invented electronic control devices for guided missiles, IBM computers, and the control unit for a pacemaker. Because you can fire it from a disstance.

Blog Post# 3

1. How were Rodinia and Pangaea similar and different from each other?
They are similar because they are both connected. They are also different because Pangaea seems more connected then Rodinia

2. When did the tectonic plates appear to move the fastest? (biggest difference between two consecutive maps)
350 and 420

3. Look at Pangaea (250 million years ago). If the continents looked like Pangaea today, what would the world be like? Think about governments, sports teams and leagues, and other aspects of life.
I think we would kind of sorta be separated (I would say we would have 4 leaders at the most that are in control). I think the teams would be separated in different regions but like the Superbowl would be With all the regions. But it might be bad because if someone bomb us they would destroy us all.

4. Look at Pangaea. If you could pick any place in Pangaea to start a modern civilization, where would you pick? Why? (there is a key on the bottom of the page that explains what the little letters in the maps stand for. For example, "ar" means Arabia.)
Most Likely NA because I am already use to living here. Also because since its bigger we would probley have a bigger army and more control than other regions.

Blog post #2

1. Cambrian, Ordovician, Silurian, Devonian, Carboniferous, Permian, Triassic, Jurassic, Cretaceous, Tertiary, and Quaternary are the geologic periods in order from oldest to present.\
2. Chicken, onions, sausage, Donuts, Carrots, Pasta, Tacos, Juice, Cookies, Tea, Quakers is so i can rember # 2
3. D,A,E,B,C are the rock layers in order from the image on the right.

Blog post#6

I think I should have a 89 for my blog post. Because I worked hard on them and because I am very cool and i know Mr. Dunn thinks I am cool too also because i did all six(including This one). I think my first one is one of my best because I like how i talked about if the space is truly infinite then there is an another earth where am wearing different stuff and look different.

Blogpost#5

1) We use sedimentary rock coal by using electricity

2) We use Igneous by riding on the road

3) One metamorphic rock is Marble, and we use it by making tile for the bathroom

4) Up above is a cool looking sedimentary rock

Blog #4

I would recommend the Chevy avalanche because it is a very nice truck. Also it is not that expensive then most cars but still up there. It is also nice because I like big trucks and also it would be a great truck to get to pick up chicks because most girls like big trucks and also because it is very stylish.

Blog Post #3

I have used Copper because i have used pennys before. I have also used a Diamond because I have used a saw. I hace used Galena because I use pencials. I have used Halite because i have used Salt. I have also used Silver because I have had Jewelry.

Blog Post #2

I like the Robinson map because it has a unique look. Also it was the sysmbol for cpt. planet. It is also usefull to show distances, sizes, and shapes accurately. Also I like the way it looks because if it were on a shirt it would look like it would almost pop out of the shirt.

Blog Post #1

Astronomy because i think it is very cool learning about space. I would like to learn about the planets and how big space is. I would also like to learn about if space truly doesn't end if so does that mean that is there another world that is the same like the one we live in but the different is that maybe i wore blue in stead of red. also maybe that yesterday is harping over again? Maybe also if aliens are real or not?